The requirements for a microbe is considered a probiotic are simple. The microbe must be alive when administered, must be documented to have a health benefit and should be administered at levels shown to confer the benefit.

A report on “Guidelines for the Evaluation of Probiotics in Food” is more complete than minimum charges probiotic experienced a necessity.

The results were:

* The Probiotics must be identified in the genus, species and strain level, using appropriate molecular and physiological techniques.

* The strain must be registered in an internationally recognized collection of crops so that scientists can duplicate the published research on the strain.

* Tests in vitro and in appropriate animals should be conducted to better understand the physiological properties of strain. However, the choice of what tests should be based, is relevant to the role probiotics offered. You should take care not to overstretch the findings of in vitro and animal tests have not been validated and has not been shown to be important in the host.

* Before use, the safety of the microbe must be considered thoroughly.

* Controlled studies should be conducted to document a health benefit on the host.

* Ability to keep alive the probiotic at the levels required in the final product through the lifetime.

Those with some familiarity in this field may notice that this list of requirements does not include such qualities as ability to attach to intestinal cells, resistance to bile and acid, bacteriocin production, anti-pathogen activity, man, to survive intestinal transit , among others. This is because the array of potential targets for health, hosts, and methods of delivery are so diverse that any property beyond those listed above is important for only a subset of probiotics, or because it is unclear whether these benefits are truly predictive of the functionality in vitro.

For example, it mentions that the probiotic to survive intestinal transit to be effective. Although there is no doubt that the ability of probiotics to grow and metabolize according to transit the intestinal tract may contribute to sickness benefits, there are also cases where this may not be necessary. For example, preliminary research suggests that some probiotics can reduce levels of Streptococcus mutans, the cause of dental caries, oral microbial community. A health benefit of this type require no survival through the gut.

At least the probiotics should be safe, effective, and should maintain its effectiveness and power through the end of shelf life. This requires a responsible approach by the producer and consumer. The producer must identify strains and storage conditions that will ensure consumers that live probiotic levels remain effective through the end of life. Consumers should store and use the product according to manufacturer’s instructions.

Source: www.articuloz.com/otros-articulos/que-hace-un-probiotico-972834.html
image source: www.salmonellablog.com/uploads/image/probiotics.jpg

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The wall lining of the gastrointestinal tract is constantly in contact with microorganisms or ingested food. About five hundred species of bacteria live in the adult gastrointestinal tract, mainly in the large intestine.

This community of microbes not only live in peaceful coexistence with humans, but also plays an important role in the welfare of the individual. There is a constant and complex interaction between these bacteria, cells in the intestine and immune system.

Probiotics are defined as live microorganisms which, when administered in adequate amounts, confer a beneficial effect on health of people.

The most frequently used probiotics are bacteria of the genus Lactobacillus and Bifidobacterium that are part of normal healthy bowel. Other probiotics include yeasts.

Probiotics show strain-specific differences in their resistance to acid and bile, ability to colonize the gastrointestinal tract and its clinical efficacy.

The effects of probiotics may be due to several mechanisms of action, including the overgrowth of harmful bacteria, blocking junctions of these bacteria to the bowel wall, increased mucus and regulation of intestinal immune response.

Currently, probiotics are widely sold in capsules, powders and functional foods such as fermented milks and yogurts.

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