Archive for the ‘Chronic Lymphocytic Leukemia’ Category
Chronic lymphocytic leukemia: Staging
Stage 0
The treatment of chronic lymphocytic leukemia stage 0 usually involves careful observation.
Stage I
The treatment of chronic lymphocytic leukemia stage I can include the following:
- Make careful observations when the number of symptoms is low or no symptoms.
- Chemotherapy with one or more drugs, with or without steroids.
- Low doses of external radiation in areas of the body affected by cancer, such as the spleen or lymph nodes.
- A clinical trial with monoclonal antibodies.
- A clinical trial of chemotherapy and transplantation of primary cells.
Stage II
The treatment of chronic lymphocytic leukemia stage II can include the following:
- Make careful observations when symptoms are scarce or nonexistent.
- Chemotherapy with one or more drugs, with or without steroids.
- Low doses of external radiation in areas of the body affected by cancer, such as the spleen or lymph nodes.
- Radiation therapy to the spleen as palliative therapy to relieve symptoms and improve quality of life.
- A clinical trial with monoclonal antibodies.
- A clinical trial of chemotherapy and transplantation of primary cells.
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This type of stem cell has already been used in treating leukemia and other blood disorders, that is the case BSCU objective, develop a plan to treat hematological disorders. First blood is drawn Cord and then separate the adult stem cells are frozen to be used for future insured children in the organization.
A part of this development the scientists say, or also give rise to blood cells do not like liver and other similar to neurons and other brain cells. However, scientists who have worked with adult stem cells continue to face major obstacles. These cells are scarce and difficult to recognize, but at least, any medical benefits that may not be reporting at the expense of the destruction of human embryos.
In addition to adult stem cells and embryonic stem cells have also been isolated embryonic germ cells. This type of stem cell derived from the gonadal ridge cells from embryos or fetuses, which produce eggs or sperm (the gonadal ridge turns into the ovaries or testes). Although embryonic germ stem cells differ from embryonic stem cells in many respects. Both institutions and others are pluripotent, ie able to generate almost all types of human cells. This potential becomes a very attractive candidate both in the creation of medical treatment without appropriate. As taken from embryos or aborted fetuses, their preparation requires the destruction of the embryo or fetus.
Have identified some risk of regenerative medicine and in the case lies in the rejection of foreign tissue by the patient’s immune system, one of the current solutions is to administer powerful drugs that suppress the immune system, but such substances have grave side effects. Another possibility would be to use stem cells taken from the patient’s own tissue as in the above case of childhood acute lymphocytic leukemia.
The solution that some scientists have proposed for the problem of immune rejection is to clone the patients, but only allow the clone to develop to the blastocyst stage, when you can extract embryonic stem cells in regenerative medicine must first discover how the body does not reject them.
Chronic lymphocytic leukemia
Chronic lymphocytic leukemia (CLL) causes a slow increase in the number of white blood cells called B lymphocytes or B cells in the bone marrow. Cancer cells spread from the marrow to the blood and may also affect the lymph nodes and other organs like the liver and spleen. This type of leukemia eventually causes the bone marrow, causing low blood counts, and weakens the immune system.
It is not known why this increase in B cells and there is no link to radiation, chemical carcinogens or viruses.
Chronic lymphocytic leukemia mainly affects adults. The average age of a patient with this type of leukemia is 70 years and is rarely seen in people younger than 40 years. The disease is more common in Jews of Russian or Eastern Europe and is rare in Asians.
Here is a considerable amount of Auer rods, which are only found in acute myeloid leukemia’s, either myeloblastic or monoblastic. These rods consist of clumps of azurophilic granules.
Treatment of chronic lymphocytic leukemia
Different types of treatment available for patients with chronic lymphocytic leukemia. Some treatments are standard (the currently used treatment) and some are being tested in clinical trials. Before starting treatment, patients should consider participating in a clinical trial.
A treatment clinical trial is a research study designed to improve current treatments or obtain information on new treatments for cancer patients. When clinical trials show that a new treatment is better than treatment “standard”, the new treatment may become standard.